Gut environment-induced intraepithelial autoreactive CD4+ T cells suppress central nervous system au...
Gut environment-induced intraepithelial autoreactive CD4+ T cells suppress central nervous system autoimmunity via LAG-3
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The gut environment has been found to significantly influence autoimmune diseases such as multiple sclerosis; however, immune cell mechanisms are unclear. Here we show that the gut epithelium of myelin oligodendrocyte glycoprotein(35-55)-specific T-cell receptor transgenic mice contains environmental stimuli-induced intraepithelial lymphocytes (IEL...
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Full title
Gut environment-induced intraepithelial autoreactive CD4+ T cells suppress central nervous system autoimmunity via LAG-3
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TN_cdi_doaj_primary_oai_doaj_org_article_71209c17bb16432bb7ba84d38a0646fd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71209c17bb16432bb7ba84d38a0646fd
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11639
