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Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71dbdedc40fa404b962276780906a9a8

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

About this item

Full title

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-09, Vol.9 (1), p.3708-8, Article 3708

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Oligodendrocyte dysfunction underlies many neurological disorders, but rapid assessment of mutation-specific effects in these cells has been impractical. To enable functional genetics in oligodendrocytes, here we report a highly efficient method for generating oligodendrocytes and their progenitors from mouse embryonic and induced pluripotent stem...

Alternative Titles

Full title

Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_71dbdedc40fa404b962276780906a9a8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71dbdedc40fa404b962276780906a9a8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-06102-7

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