Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Oligodendrocyte dysfunction underlies many neurological disorders, but rapid assessment of mutation-specific effects in these cells has been impractical. To enable functional genetics in oligodendrocytes, here we report a highly efficient method for generating oligodendrocytes and their progenitors from mouse embryonic and induced pluripotent stem...
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Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_71dbdedc40fa404b962276780906a9a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71dbdedc40fa404b962276780906a9a8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06102-7