Olaparib modulates DNA repair efficiency, sensitizes cervical cancer cells to cisplatin and exhibits...
Olaparib modulates DNA repair efficiency, sensitizes cervical cancer cells to cisplatin and exhibits anti-metastatic property
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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PARP1 trapping at DNA lesion by pharmacological inhibitors has been exploited in several cancers exhibiting defects in DNA repair mechanisms. PARP1 hyperactivation is involved in therapeutic resistance in multiple cancers. The role of PARP1 in cervical cancer (CC) resistance and implication of PARP inhibitor is yet to be elucidated. Our data demons...
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Olaparib modulates DNA repair efficiency, sensitizes cervical cancer cells to cisplatin and exhibits anti-metastatic property
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TN_cdi_doaj_primary_oai_doaj_org_article_7245be15cdae4da18b1280c3537d3242
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7245be15cdae4da18b1280c3537d3242
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-13232-3
