Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-r...
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm
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Author / Creator
Guo, Chuang , Li, Bin , Ma, Huan , Wang, Xiaofang , Cai, Pengfei , Yu, Qiaoni , Zhu, Lin , Jin, Liying , Jiang, Chen , Fang, Jingwen , Liu, Qian , Zong, Dandan , Zhang, Wen , Lu, Yichen , Li, Kun , Gao, Xuyuan , Fu, Binqing , Liu, Lianxin , Ma, Xiaoling , Weng, Jianping , Wei, Haiming , Jin, Tengchuan , Lin, Jun and Qu, Kun
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Several studies show that the immunosuppressive drugs targeting the interleukin-6 (IL-6) receptor, including tocilizumab, ameliorate lethal inflammatory responses in COVID-19 patients infected with SARS-CoV-2. Here, by employing single-cell analysis of the immune cell composition of two severe-stage COVID-19 patients prior to and following tocilizu...
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Full title
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_725c63210c6543e5bbfeb15fc0ba1839
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_725c63210c6543e5bbfeb15fc0ba1839
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17834-w
