Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Malaria inflicts an enormous burden on global human health. The emergence of parasite resistance to front-line drugs has prompted a renewed focus on the repositioning of clinically approved drugs as potential anti-malarial therapies. Antibiotics that inhibit protein translation are promising candidates for repositioning. We have solved the cryo-EM...
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Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine
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TN_cdi_doaj_primary_oai_doaj_org_article_72b622919455418cb8c2c9e4f74f25b6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72b622919455418cb8c2c9e4f74f25b6
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.03080