Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angio...
Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Alzheimer Disease (AD) and cerebral amyloid angiopathy (CAA) are both characterized by amyloid-β (Aβ) accumulation in the brain, although Aβ deposits mostly in the brain parenchyma in AD and in the cerebrovasculature in CAA. The presence of CAA can exacerbate clinical outcomes of AD patients by promoting spontaneous intracerebral hemorrhage and isc...
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Full title
Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_7341764dc8e949829a64d14fa44fbf34
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7341764dc8e949829a64d14fa44fbf34
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-023-00610-x
