Effect of the ROCK inhibitor fasudil on the brain proteomic profile in the tau transgenic mouse mode...
Effect of the ROCK inhibitor fasudil on the brain proteomic profile in the tau transgenic mouse model of Alzheimer's disease
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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The goal of this study is to explore the pharmacological potential of the amyloid-reducing vasodilator fasudil, a selective Ras homolog (Rho)-associated kinases (ROCK) inhibitor, in the P301S tau transgenic mouse model (Line PS19) of neurodegenerative tauopathy and Alzheimer's disease (AD).
We used LC-MS/MS, ELISA and bioinformatic approaches to...
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Effect of the ROCK inhibitor fasudil on the brain proteomic profile in the tau transgenic mouse model of Alzheimer's disease
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TN_cdi_doaj_primary_oai_doaj_org_article_738526ed29cf4602848657bb379d4868
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_738526ed29cf4602848657bb379d4868
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2024.1323563
