Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism...
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Sciatic nerve crush injury triggers sterile inflammation within the distal nerve and axotomized dorsal root ganglia (DRGs). Granulocytes and pro-inflammatory Ly6C
monocytes infiltrate the nerve first and rapidly give way to Ly6C
inflammation-resolving macrophages. In axotomized DRGs, few hematogenous leukocytes are detected and resident macro...
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Full title
Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement
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TN_cdi_doaj_primary_oai_doaj_org_article_73c8db5f0a594201b278cc63aa1ceee2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_73c8db5f0a594201b278cc63aa1ceee2
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.60223
