T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine
T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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IL-23 is a key driver of pathogenic Th17 cell responses. It has been suggested that the transcription factor T-bet is required to facilitate IL-23-driven pathogenic effector functions; however, the precise role of T-bet in intestinal T cell responses remains elusive. Here, we show that T-bet expression by T cells is not required for the induction o...
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T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine
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TN_cdi_doaj_primary_oai_doaj_org_article_7468206667654e0d9f30482bda325b7b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7468206667654e0d9f30482bda325b7b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11627
