A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold...
A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response
About this item
Full title
Author / Creator
Lainšček, Duško , Fink, Tina , Forstnerič, Vida , Hafner-Bratkovič, Iva , Orehek, Sara , Strmšek, Žiga , Manček-Keber, Mateja , Pečan, Peter , Esih, Hana , Malenšek, Špela , Aupič, Jana , Dekleva, Petra , Plaper, Tjaša , Vidmar, Sara , Kadunc, Lucija , Benčina, Mojca , Omersa, Neža , Anderluh, Gregor , Pojer, Florence , Lau, Kelvin , Hacker, David , Correia, Bruno E. , Peterhoff, David , Wagner, Ralf , Bergant, Valter , Herrmann, Alexander , Pichlmair, Andreas and Jerala, Roman
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
The response of the adaptive immune system is augmented by multimeric presentation of a specific antigen, resembling viral particles. Several vaccines have been designed based on natural or designed protein scaffolds, which exhibited a potent adaptive immune response to antigens; however, antibodies are also generated against the scaffold, which ma...
Alternative Titles
Full title
A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response
Authors, Artists and Contributors
Author / Creator
Fink, Tina
Forstnerič, Vida
Hafner-Bratkovič, Iva
Orehek, Sara
Strmšek, Žiga
Manček-Keber, Mateja
Pečan, Peter
Esih, Hana
Malenšek, Špela
Aupič, Jana
Dekleva, Petra
Plaper, Tjaša
Vidmar, Sara
Kadunc, Lucija
Benčina, Mojca
Omersa, Neža
Anderluh, Gregor
Pojer, Florence
Lau, Kelvin
Hacker, David
Correia, Bruno E.
Peterhoff, David
Wagner, Ralf
Bergant, Valter
Herrmann, Alexander
Pichlmair, Andreas
Jerala, Roman
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_74784734a4764cf7add9be42d5336cc7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74784734a4764cf7add9be42d5336cc7
Other Identifiers
ISSN
2076-393X
E-ISSN
2076-393X
DOI
10.3390/vaccines9050431