Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenues
Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenues
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Tauopathies are disorders associated with tau protein dysfunction and insoluble tau accumulation in the brain at autopsy. Multiple lines of evidence from human disease, as well as nonclinical translational models, suggest that tau has a central pathologic role in these disorders, historically thought to be primarily related to tau gain of toxic fun...
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Full title
Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenues
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TN_cdi_doaj_primary_oai_doaj_org_article_7490322713b34eb3ac83d8b54342a9e2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7490322713b34eb3ac83d8b54342a9e2
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI168553
