Timing is everything: structural insights into the disease-linked Kv3 channels controlling fast acti...
Timing is everything: structural insights into the disease-linked Kv3 channels controlling fast action-potential firing in the brain
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Kv3 channels enable neurons to fire at very high frequencies (>100 Hz) which is fundamental to brain development and our ability to make sense of the world at large. Cryo-EM and structure-function studies by Chi et al. now uncover Kv3 channel gating mechanisms and support new precision medicine approaches for CNS diseases.
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Timing is everything: structural insights into the disease-linked Kv3 channels controlling fast action-potential firing in the brain
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TN_cdi_doaj_primary_oai_doaj_org_article_74a144cdc8904c67921403b5232489bb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74a144cdc8904c67921403b5232489bb
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31537-4
