Elevated plasma neurofilament light in aging reflects brain white‐matter alterations but does not pr...
Elevated plasma neurofilament light in aging reflects brain white‐matter alterations but does not predict cognitive decline or Alzheimer's disease
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Publisher
United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
Introduction
We investigated neurofilament light (NFL) accumulation in normal aging as well as in preclinical and clinical Alzheimer's disease (AD) and assessed individual differences in NFL load in relation to cognition and brain white‐matter integrity.
Methods
We analyzed longitudinal data covering 30 years (1988–2017). Cognitive testing...
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Full title
Elevated plasma neurofilament light in aging reflects brain white‐matter alterations but does not predict cognitive decline or Alzheimer's disease
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TN_cdi_doaj_primary_oai_doaj_org_article_74a85dbe53c14b108c4583916c58f209
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74a85dbe53c14b108c4583916c58f209
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ISSN
2352-8729,1552-5260,1552-5279
E-ISSN
2352-8729
DOI
10.1002/dad2.12050
