Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine
Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine
About this item
Full title
Author / Creator
Webster, Rebecca , Sekuloski, Silvana , Odedra, Anand , Woolley, Stephen , Jennings, Helen , Amante, Fiona , Trenholme, Katharine R , Healer, Julie , Cowman, Alan F , Eriksson, Emily M , Sathe, Priyanka , Penington, Jocelyn , Blanch, Adam J , Dixon, Matthew W A , Tilley, Leann , Duffy, Michael F , Craig, Alister , Storm, Janet , Chan, Jo-Anne , Evans, Krystal , Papenfuss, Anthony T , Schofield, Louis , Griffin, Paul , Barber, Bridget E , Andrew, Dean , Boyle, Michelle J , de Labastida Rivera, Fabian , Engwerda, Christian and McCarthy, James S
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
There is a clear need for novel approaches to malaria vaccine development. We aimed to develop a genetically attenuated blood-stage vaccine and test its safety, infectivity, and immunogenicity in healthy volunteers. Our approach was to target the gene encoding the knob-associated histidine-rich protein (KAHRP), which is responsible for the assembly...
Alternative Titles
Full title
Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine
Authors, Artists and Contributors
Author / Creator
Sekuloski, Silvana
Odedra, Anand
Woolley, Stephen
Jennings, Helen
Amante, Fiona
Trenholme, Katharine R
Healer, Julie
Cowman, Alan F
Eriksson, Emily M
Sathe, Priyanka
Penington, Jocelyn
Blanch, Adam J
Dixon, Matthew W A
Tilley, Leann
Duffy, Michael F
Craig, Alister
Storm, Janet
Chan, Jo-Anne
Evans, Krystal
Papenfuss, Anthony T
Schofield, Louis
Griffin, Paul
Barber, Bridget E
Andrew, Dean
Boyle, Michelle J
de Labastida Rivera, Fabian
Engwerda, Christian
McCarthy, James S
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_74cfc9b904474091b17850c1e5910004
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74cfc9b904474091b17850c1e5910004
Other Identifiers
ISSN
1741-7015
E-ISSN
1741-7015
DOI
10.1186/s12916-021-02150-x
