SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomi...
SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background The mechanism by which glioblastoma evades temozolomide (TMZ)-induced cytotoxicity is largely unknown. We hypothesized that mitochondria plays a role in this process. Methods RNA transcriptomes were obtained from tumor samples and online databases. Expression of different proteins was manipulated using RNA interference or gene amplificat...
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SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_74d3093ae005449f902018ee36784041
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74d3093ae005449f902018ee36784041
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02429-8
