Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit
Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Microtubules (MTs) are key components of the cytoskeleton and play a central role in cell division and development. MT assembly is known to be associated with a structural change in [Formula: see text]-tubulin dimers from kinked to straight conformations. How GTP binding renders individual dimers polymerization-competent, however, is still unclear....
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Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit
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TN_cdi_doaj_primary_oai_doaj_org_article_7579f833675b483d9219c0aa8e3b95eb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7579f833675b483d9219c0aa8e3b95eb
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.34353
