CDK1 dependent phosphorylation of hTERT contributes to cancer progression
CDK1 dependent phosphorylation of hTERT contributes to cancer progression
About this item
Full title
Author / Creator
Yasukawa, Mami , Ando, Yoshinari , Yamashita, Taro , Matsuda, Yoko , Shoji, Shisako , Morioka, Masaki Suimye , Kawaji, Hideya , Shiozawa, Kumiko , Machitani, Mitsuhiro , Abe, Takaya , Yamada, Shinji , Kaneko, Mika K. , Kato, Yukinari , Furuta, Yasuhide , Kondo, Tadashi , Shirouzu, Mikako , Hayashizaki, Yoshihide , Kaneko, Shuichi and Masutomi, Kenkichi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The telomerase reverse transcriptase is upregulated in the majority of human cancers and contributes directly to cell transformation. Here we report that hTERT is phosphorylated at threonine 249 during mitosis by the serine/threonine kinase CDK1. Clinicopathological analyses reveal that phosphorylation of hTERT at threonine 249 occurs more frequent...
Alternative Titles
Full title
CDK1 dependent phosphorylation of hTERT contributes to cancer progression
Authors, Artists and Contributors
Author / Creator
Ando, Yoshinari
Yamashita, Taro
Matsuda, Yoko
Shoji, Shisako
Morioka, Masaki Suimye
Kawaji, Hideya
Shiozawa, Kumiko
Machitani, Mitsuhiro
Abe, Takaya
Yamada, Shinji
Kaneko, Mika K.
Kato, Yukinari
Furuta, Yasuhide
Kondo, Tadashi
Shirouzu, Mikako
Hayashizaki, Yoshihide
Kaneko, Shuichi
Masutomi, Kenkichi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_761b43ac125a4eb99158e2f0b22fb7cd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_761b43ac125a4eb99158e2f0b22fb7cd
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15289-7
