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ArticlesPeer ReviewedFull Text
RNA‐dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID‐19
Author / Creator:Machitani, Mitsuhiro ; Yasukawa, Mami ; Nakashima, Jotaro ; Furuichi, Yasuhiro ; Masutomi, Kenkichi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2020-11, Vol.111 (11), p.3976-3984
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ArticlesPeer ReviewedFull Text
CDK1 dependent phosphorylation of hTERT contributes to cancer progression
Author / Creator:Yasukawa, Mami ; Ando, Yoshinari ; Yamashita, Taro ; Matsuda, Yoko ; Shoji, Shisako ; Morioka, Masaki Suimye ; Kawaji, Hideya ; Shiozawa, Kumiko ; Machitani, Mitsuhiro ; Abe, Takaya ; Yamada, Shinji ; Kaneko, Mika K. ; Kato, Yukinari ; Furuta, Yasuhide ; Kondo, Tadashi ; Shirouzu, Mikako ; Hayashizaki, Yoshihide ; Kaneko, Shuichi ; Masutomi, Kenkichi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-03, Vol.11 (1), p.1557-18, Article 1557
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ArticlesPeer ReviewedFull Text
Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2
Author / Creator:Machitani, Mitsuhiro ; Takei, Junko ; Kaneko, Mika K. ; Ueki, Saori ; Ohashi, Hirofumi ; Watashi, Koichi ; Kato, Yukinari ; Masutomi, Kenkichi
Publisher:England: BioMed Central Ltd
Journal title:Virology journal, 2022-12, Vol.19 (1), p.213-213, Article 213
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ArticlesPeer ReviewedFull Text
Dicer functions as an antiviral system against human adenoviruses via cleavage of adenovirus-encoded noncoding RNA
Author / Creator:Machitani, Mitsuhiro ; Sakurai, Fuminori ; Wakabayashi, Keisaku ; Tomita, Kyoko ; Tachibana, Masashi ; Mizuguchi, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-06, Vol.6 (1), p.27598-27598, Article 27598
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ArticlesPeer ReviewedFull Text
Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration
Author / Creator:Tomita, Kyoko ; Sakurai, Fuminori ; Iizuka, Shunsuke ; Hemmi, Masahisa ; Wakabayashi, Keisaku ; Machitani, Mitsuhiro ; Tachibana, Masashi ; Katayama, Kazufumi ; Kamada, Haruhiko ; Mizuguchi, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-08, Vol.8 (1), p.12315-12, Article 12315
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ArticlesPeer ReviewedFull Text
Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition of Dicer-Mediated Processing to Small Interfering RNA
Author / Creator:Machitani, Mitsuhiro ; Sakurai, Fuminori ; Wakabayashi, Keisaku ; Takayama, Kosuke ; Tachibana, Masashi ; Mizuguchi, Hiroyuki
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2017-03, Vol.6, p.173-182
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ArticlesPeer ReviewedFull Text
Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus
Author / Creator:Sakurai, Fuminori ; Narii, Nobuhiro ; Tomita, Kyoko ; Togo, Shinsaku ; Takahashi, Kazuhisa ; Machitani, Mitsuhiro ; Tachibana, Masashi ; Ouchi, Masaaki ; Katagiri, Nobuyoshi ; Urata, Yasuo ; Fujiwara, Toshiyoshi ; Mizuguchi, Hiroyuki
Publisher:United States: Elsevier Limited
Journal title:Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16001-16001, Article 16001
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ArticlesPeer ReviewedFull Text
Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity
Author / Creator:Machitani, Mitsuhiro ; Nomura, Akira ; Yamashita, Taro ; Yasukawa, Mami ; Ueki, Saori ; Fujita, Ken-Ichi ; Ueno, Toshihide ; Yamashita, Akio ; Tanzawa, Yoshikazu ; Watanabe, Masahiko ; Taniguchi, Toshiyasu ; Saitoh, Noriko ; Kaneko, Shuichi ; Kato, Yukinari ; Mano, Hiroyuki ; Masutomi, Kenkichi
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2024-06, Vol.26 (6), p.932-945
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ArticlesPeer ReviewedFull Text
Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition of Dicer-Mediated Processing to Small Interfering RNA Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition...
Author / Creator:Mitsuhiro Machitani ; Fuminori Sakurai ; Keisaku Wakabayashi ; Kosuke Takayama ; Masashi Tachibana ; Hiroyuki Mizuguchi
Publisher:Elsevier
Journal title:Molecular therapy. Nucleic acids, 2017-03, Vol.6, p.173-182
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ArticlesPeer ReviewedFull Text
Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB
Author / Creator:Machitani, Mitsuhiro ; Sakurai, Fuminori ; Wakabayashi, Keisaku ; Nakatani, Kosuke ; Tachibana, Masashi ; Kato, Nobuyuki ; Fujiwara, Toshiyoshi ; Mizuguchi, Hiroyuki
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Oncolytics, 2017-12, Vol.7, p.76-85
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ReviewsPeer ReviewedFull Text
Adenovirus Vector-Derived VA-RNA-Mediated Innate Immune Responses
Author / Creator:Machitani, Mitsuhiro ; Yamaguchi, Tomoko ; Shimizu, Kahori ; Sakurai, Fuminori ; Katayama, Kazufumi ; Kawabata, Kenji ; Mizuguchi, Hiroyuki
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceutics, 2011, Vol.3 (3), p.338-353
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ArticlesFull Text
Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB
Author / Creator:Mitsuhiro Machitani ; Fuminori Sakurai ; Keisaku Wakabayashi ; Kosuke Nakatani ; Masashi Tachibana ; Nobuyuki Kato ; Toshiyoshi Fujiwara ; Hiroyuki Mizuguchi
Publisher:Elsevier
Journal title:Molecular therapy. Oncolytics, 2017-12, Vol.7, p.76-85
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RNA‐dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID‐19

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CDK1 dependent phosphorylation of hTERT contributes to cancer progression

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Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2

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Dicer functions as an antiviral system against human adenoviruses via cleavage of adenovirus-encoded noncoding RNA

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Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration

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Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition of Dicer-Mediated Processing to Small Interfering RNA

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Efficient detection of human circulating tumor cells without significant production of false-positive cells by a novel conditionally replicating adenovirus

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Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity

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Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition of Dicer-Mediated Processing to Small Interfering RNA Type I Interferons Impede Short Hairpin RNA-Mediated RNAi via Inhibition...

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Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB

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Adenovirus Vector-Derived VA-RNA-Mediated Innate Immune Responses

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Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB

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