Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of n...
Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray
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Publisher
England: The Company of Biologists Ltd
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Language
English
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Publisher
England: The Company of Biologists Ltd
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Contents
The Smyd1 gene encodes a lysine methyltransferase specifically expressed in striated muscle. Because Smyd1-null mouse embryos die from heart malformation prior to formation of skeletal muscle, we developed a Smyd1 conditional-knockout allele to determine the consequence of SMYD1 loss in mammalian skeletal muscle. Ablation of SMYD1 specifically in s...
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Full title
Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray
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TN_cdi_doaj_primary_oai_doaj_org_article_7624d789c2964ec3942e5143c4307fb0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7624d789c2964ec3942e5143c4307fb0
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.022491
