The role of pathological tau in synaptic dysfunction in Alzheimer's diseases
The role of pathological tau in synaptic dysfunction in Alzheimer's diseases
About this item
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Author / Creator
Wu, Moxin , Zhang, Manqing , Yin, Xiaoping , Chen, Kai , Hu, Zhijian , Zhou, Qin , Cao, Xianming , Chen, Zhiying and Liu, Dan
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline, accompanied by amyloid-β (Aβ) overload and hyperphosphorylated tau accumulation in the brain. Synaptic dysfunction, an important pathological hallmark in AD, is recognized as the main cause of the cognitive impairments. Accumulating evidence sugg...
Alternative Titles
Full title
The role of pathological tau in synaptic dysfunction in Alzheimer's diseases
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_765eab5126d74de6b3567f70393b2d75
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_765eab5126d74de6b3567f70393b2d75
Other Identifiers
ISSN
2047-9158
E-ISSN
2047-9158
DOI
10.1186/s40035-021-00270-1
