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Deep learning-based aberration compensation improves contrast and resolution in fluorescence microsc...

Deep learning-based aberration compensation improves contrast and resolution in fluorescence microsc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_766d67edf8ea4d09aca345b0dd87a934

Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy

About this item

Full title

Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-01, Vol.16 (1), p.313-19, Article 313

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Optical aberrations hinder fluorescence microscopy of thick samples, reducing image signal, contrast, and resolution. Here we introduce a deep learning-based strategy for aberration compensation, improving image quality without slowing image acquisition, applying additional dose, or introducing more optics. Our method (i) introduces synthetic aberr...

Alternative Titles

Full title

Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_766d67edf8ea4d09aca345b0dd87a934

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_766d67edf8ea4d09aca345b0dd87a934

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-55267-x

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