A logical network-based drug-screening platform for Alzheimer’s disease representing pathological fe...
A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, we report an efficient, network-based drug-screening platform developed by integrating mathematical modeling and the pathological features of AD with human iPSC-derived cerebral organoids (iCOs),...
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A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids
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TN_cdi_doaj_primary_oai_doaj_org_article_76e852796f214d3b97b10bab8107b2db
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_76e852796f214d3b97b10bab8107b2db
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-20440-5
