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Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_76fd4030671b463caa29778deed50624

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

About this item

Full title

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

Publisher

England: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2020-04, Vol.17 (1), p.119-18, Article 119

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Many lines of evidence suggest that accumulation of aggregated alpha-synuclein (αSYN) in the Parkinson's disease (PD) brain causes infiltration of T cells. However, in which ways the stationary brain cells interact with the T cells remain elusive. Here, we identify astrocytes as potential antigen-presenting cells capable of activating T cells in th...

Alternative Titles

Full title

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_76fd4030671b463caa29778deed50624

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_76fd4030671b463caa29778deed50624

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-020-01776-7

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