Spontaneous and specific chemical cross-linking in live cells to capture and identify protein intera...
Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Covalently locking interacting proteins in situ is an attractive strategy for addressing the challenge of identifying weak and transient protein interactions, yet it is demanding to execute chemical reactions in live systems in a biocompatible, specific, and autonomous manner. Harnessing proximity-enabled reactivity of an unnatural amino acid incor...
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Full title
Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions
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TN_cdi_doaj_primary_oai_doaj_org_article_780166a230784b39849b98e73164024f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_780166a230784b39849b98e73164024f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02409-z
