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Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C 9 Mab-24) Using th...

Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C 9 Mab-24) Using th...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7811776e1c914ce79528504e82484541

Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C 9 Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method

About this item

Full title

Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C 9 Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method

Publisher

Switzerland: MDPI AG

Journal title

Antibodies (Basel), 2023-01, Vol.12 (1), p.11

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

C-C chemokine receptor 9 (CCR9) is a receptor for C-C-chemokine ligand 25 (CCL25). CCR9 is crucial in the chemotaxis of immune cells and inflammatory responses. Moreover, CCR9 is highly expressed in tumors, including several solid tumors and T-cell acute lymphoblastic leukemia. Several preclinical studies have shown that anti-CCR9 monoclonal antibo...

Alternative Titles

Full title

Determination of the Binding Epitope of an Anti-Mouse CCR9 Monoclonal Antibody (C 9 Mab-24) Using the 1× Alanine and 2× Alanine-Substitution Method

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7811776e1c914ce79528504e82484541

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7811776e1c914ce79528504e82484541

Other Identifiers

ISSN

2073-4468

E-ISSN

2073-4468

DOI

10.3390/antib12010011

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