143 Correlating RNA-seq detection and IHC staining of potential antibody-drug conjugate (ADC) target...
143 Correlating RNA-seq detection and IHC staining of potential antibody-drug conjugate (ADC) targets: HER3, HER2, TROP2, Nectin4, and aFLR
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundThe growing interest in antibody-drug conjugates (ADCs) as promising therapies for multiple cancer types highlights the need for accurate approaches to detect ADC targets.1 2 While the conventional method to identify ADC targets is immunohistochemistry (IHC), using RNA sequencing (RNA-seq) could help improve detection by minimizing the di...
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143 Correlating RNA-seq detection and IHC staining of potential antibody-drug conjugate (ADC) targets: HER3, HER2, TROP2, Nectin4, and aFLR
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TN_cdi_doaj_primary_oai_doaj_org_article_785b317c69ae482fa8179679339d17f1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_785b317c69ae482fa8179679339d17f1
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.0143
