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Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia

Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_78b9668d870244cca6b2f62d7f2fe96b

Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia

About this item

Full title

Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-01, Vol.15 (1), p.87-87, Article 87

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Influenza A virus (IAV) infection mobilizes bone marrow-derived macrophages (BMDM) that gradually undergo transition to tissue-resident alveolar macrophages (TR-AM) in the inflamed lung. Combining high-dimensional single-cell transcriptomics with complex lung organoid modeling, in vivo adoptive cell transfer, and BMDM-specific gene targeting, we fo...

Alternative Titles

Full title

Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_78b9668d870244cca6b2f62d7f2fe96b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_78b9668d870244cca6b2f62d7f2fe96b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-44421-6

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