Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease
Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease
About this item
Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
One of the primary genetic risk factors for Alzheimer’s disease (AD) is the presence of the Ɛ4 allele of apolipoprotein E (APOE). APOE is a polymorphic lipoprotein that is a major cholesterol carrier in the brain. It is also involved in various cellular functions such as neuronal signaling, neuroinflammation and glucose metabolism. Humans predomina...
Alternative Titles
Full title
Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_78f4708f3a3449aeb4fef1fb908ef363
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_78f4708f3a3449aeb4fef1fb908ef363
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-020-0358-9
