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Reference EntriesFull Text
Borchelt, David R
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: BAY-BUP, 2022, p.1209-1209
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Borchelt, David R
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: BEA-BUD, 2021, p.1201-1201
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ArticlesPeer ReviewedFull Text
Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease
Author / Creator:Williams, Tosha ; Borchelt, David R. ; Chakrabarty, Paramita
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2020-01, Vol.15 (1), p.8-8, Article 8
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ArticlesPeer ReviewedFull Text
Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis
Author / Creator:Staats, Kim A. ; Borchelt, David R. ; Tansey, Malú Gámez ; Wymer, James
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2022-01, Vol.17 (1), p.11-11, Article 11
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ArticlesPeer ReviewedFull Text
Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice
Author / Creator:Sacino, Amanda N. ; Brooks, Mieu ; Thomas, Michael A. ; McKinney, Alex B. ; Lee, Sooyeon ; Regenhardt, Robert W. ; McGarvey, Nicholas H. ; Ayers, Jacob I. ; Notterpek, Lucia ; Borchelt, David R. ; Golde, Todd E. ; Giasson, Benoit I.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10732-10737
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ArticlesPeer ReviewedFull Text
Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain
Author / Creator:Chakrabarty, Paramita ; Rosario, Awilda ; Cruz, Pedro ; Siemienski, Zoe ; Ceballos-Diaz, Carolina ; Crosby, Keith ; Jansen, Karen ; Borchelt, David R. ; Kim, Ji-Yoen ; Jankowsky, Joanna L. ; Golde, Todd E. ; Levites, Yona
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-06, Vol.8 (6), p.e67680-e67680
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ArticlesPeer ReviewedFull Text
Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways
Author / Creator:Ayers, Jacob I. ; Fromholt, Susan E. ; O’Neal, Veronica M. ; Diamond, Jeffrey H. ; Borchelt, David R.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2016-01, Vol.131 (1), p.103-114
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ArticlesPeer ReviewedFull Text
Thinking laterally about neurodegenerative proteinopathies
Author / Creator:Golde, Todd E. ; Borchelt, David R. ; Giasson, Benoit I. ; Lewis, Jada
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-05, Vol.123 (5), p.1847-1855
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ArticlesPeer ReviewedFull Text
Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection
Author / Creator:Crown, Anthony ; McAlary, Luke ; Fagerli, Eric ; Brown, Hilda ; Yerbury, Justin J. ; Galaleldeen, Ahmad ; Cashman, Neil R. ; Borchelt, David R. ; Ayers, Jacob I.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-01, Vol.15 (1), p.e0227655
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ArticlesPeer ReviewedFull Text
Remodeling Alzheimer-amyloidosis models by seeding
Author / Creator:Ulm, Brittany S. ; Borchelt, David R. ; Moore, Brenda D.
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2021-02, Vol.16 (1), p.8-8, Article 8
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Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS
Author / Creator:Chang, Yueming ; Kong, Qiongman ; Shan, Xiu ; Tian, Guilian ; Ilieva, Hristelina ; Cleveland, Don W. ; Rothstein, Jeffrey D. ; Borchelt, David R. ; Wong, Philip C. ; Lin, Chien-liang Glenn
Publisher:United States: Public Library of Science
Journal title:PloS one, 2008-08, Vol.3 (8), p.e2849-e2849
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ArticlesPeer ReviewedFull Text
Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease
Author / Creator:Pace, Michael C. ; Xu, Guilian ; Fromholt, Susan ; Howard, John ; Crosby, Keith ; Giasson, Benoit I. ; Lewis, Jada ; Borchelt, David R.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2018-12, Vol.136 (6), p.919-938
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ArticlesPeer ReviewedFull Text
Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS
Author / Creator:Ayers, Jacob I. ; Diamond, Jeffrey ; Sari, Adriana ; Fromholt, Susan ; Galaleldeen, Ahmad ; Ostrow, Lyle W. ; Glass, Jonathan D. ; Hart, P. John ; Borchelt, David R.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2016-12, Vol.132 (6), p.827-840
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ArticlesPeer ReviewedFull Text
Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice
Author / Creator:Ayers, Jacob I. ; Xu, Guilian ; Lu, Qing ; Dillon, Kristy ; Fromholt, Susan ; Borchelt, David R.
Publisher:Basel: MDPI AG
Journal title:Viruses, 2023-08, Vol.15 (9), p.1819
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ArticlesPeer ReviewedFull Text
Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS
Author / Creator:Karch, Celeste M ; Prudencio, Mercedes ; Winkler, Duane D ; Hart, P. John ; Borchelt, David R
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (19), p.7774-7779
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ArticlesPeer ReviewedFull Text
Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer’s Disease
Author / Creator:Xu, Guilian ; Fromholt, Susan ; Borchelt, David R.
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2022-06, Vol.12 (7), p.886
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ArticlesPeer ReviewedFull Text
Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy
Author / Creator:Gallego-Iradi, M. Carolina ; Clare, Alexis M. ; Brown, Hilda H. ; Janus, Christopher ; Lewis, Jada ; Borchelt, David R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-11, Vol.10 (11), p.e0142144-e0142144
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ArticlesPeer ReviewedFull Text
Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau
Author / Creator:Smith, Ethan D. ; Vo, Quan ; Giasson, Benoit I. ; Borchelt, David R. ; Prokop, Stefan ; Chakrabarty, Paramita
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2023-10, Vol.11 (1), p.172-172, Article 172
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ArticlesPeer ReviewedFull Text
Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model
Author / Creator:Lloyd, Grace M. ; Dhillon, Jess-Karan S. ; Gorion, Kimberly-Marie M. ; Riffe, Cara ; Fromholt, Susan E. ; Xia, Yuxing ; Giasson, Benoit I. ; Borchelt, David R.
Publisher:England: BioMed Central
Journal title:Molecular neurodegeneration, 2021-09, Vol.16 (1), p.63-17, Article 63
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ArticlesPeer ReviewedFull Text
Correction: Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model
Author / Creator:Lloyd, Grace M. ; Dhillon, Jess-Karan S. ; Gorion, Kimberly-Marie M. ; Riffe, Cara ; Fromholt, Susan E. ; Xia, Yuxing ; Giasson, Benoit I. ; Borchelt, David R.
Publisher:England: BioMed Central
Journal title:Molecular neurodegeneration, 2024-02, Vol.19 (1), p.17-17, Article 17
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Borchelt, David R

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Borchelt, David R

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Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease

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Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis

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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice

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Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

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Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways

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Thinking laterally about neurodegenerative proteinopathies

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Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection

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Remodeling Alzheimer-amyloidosis models by seeding

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Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS

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Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease

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Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS

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Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice

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Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS

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Modeling the Competition between Misfolded Aβ Conformers That Produce Distinct Types of Amyloid Pathology in Alzheimer’s Disease

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Subcellular Localization of Matrin 3 Containing Mutations Associated with ALS and Distal Myopathy

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Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau

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Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model

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Correction: Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model

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