Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with...
Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Immune checkpoint blockade (ICB) therapy has revolutionized the treatment of lung squamous cell carcinoma (LUSC). However, a significant proportion of patients with high tumour PD-L1 expression remain resistant to immune checkpoint inhibitors. To understand the underlying resistance mechanisms, characterization of the immunosuppressive t...
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Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance
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TN_cdi_doaj_primary_oai_doaj_org_article_7aac86769e03422cba9598766b752c83
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7aac86769e03422cba9598766b752c83
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1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-022-01079-x