Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes
Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Systematic search for genes whose gain-of-function by exogenous expression confers an advantage in cell-based selective screenings is a powerful method for unbiased functional exploration of the genome, and has the potential to disclose new targets for cancer therapy. A major limit of this approach resides in the labor-intensive cloning of resistan...
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Full title
Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes
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TN_cdi_doaj_primary_oai_doaj_org_article_7aae0ffc2d7b47009625130b2ba27b01
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7aae0ffc2d7b47009625130b2ba27b01
Other Identifiers
ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/1471-2164-9-254
