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Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity

Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b1db259dd90464b97f9fe943413dea6

Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity

About this item

Full title

Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2019-05, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Enhancers are important regulatory elements that can control gene activity across vast genetic distances. However, the underlying nature of this regulation remains obscured because it has been difficult to observe in living cells. Here, we visualize the spatial organization and transcriptional output of the key pluripotency regulator
and its ess...

Alternative Titles

Full title

Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7b1db259dd90464b97f9fe943413dea6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b1db259dd90464b97f9fe943413dea6

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.41769

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