A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secre...
A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secretion
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Exosomes are secreted to the extracellular milieu when multivesicular endosomes (MVEs) dock and fuse with the plasma membrane. However, MVEs are also known to fuse with lysosomes for degradation. How MVEs are directed to the plasma membrane for exosome secretion rather than to lysosomes is unclear. Here we report that a conversion of phosphatidylin...
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Full title
A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secretion
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TN_cdi_doaj_primary_oai_doaj_org_article_7b22fef705c44cdfacac9cdba58c3572
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7b22fef705c44cdfacac9cdba58c3572
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42661-0
