Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occu...
Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Polycomb repressive complex 1 (PRC1) is an essential chromatin-based repressor of gene transcription. How PRC1 engages with chromatin to identify its target genes and achieve gene repression remains poorly defined, representing a major hurdle to our understanding of Polycomb system function. Here, we use genome engineering and single particle track...
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Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy
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TN_cdi_doaj_primary_oai_doaj_org_article_7bacb3f5063e4e4d8aafcc969a45c153
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7bacb3f5063e4e4d8aafcc969a45c153
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21130-6
