Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus erythematosus pat...
Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus erythematosus patients identifies ethnicity- and disease-specific expression signatures
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Systemic lupus erythematosus (SLE) is an autoimmune disease in which outcomes vary among different racial groups. We leverage cell-sorted RNA-seq data (CD14+ monocytes, B cells, CD4+ T cells, and NK cells) from 120 SLE patients (63 Asian and 57 White individuals) and apply a four-tier approach including unsupervised clustering, differential express...
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Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus erythematosus patients identifies ethnicity- and disease-specific expression signatures
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TN_cdi_doaj_primary_oai_doaj_org_article_7bed769c8e6e4805aebc706b9462c06e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7bed769c8e6e4805aebc706b9462c06e
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02000-9
