Nucleolar release of rDNA repeats for repair involves SUMO-mediated untethering by the Cdc48/p97 seg...
Nucleolar release of rDNA repeats for repair involves SUMO-mediated untethering by the Cdc48/p97 segregase
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Ribosomal RNA genes (rDNA) are highly unstable and susceptible to rearrangement due to their repetitive nature and active transcriptional status. Sequestration of rDNA in the nucleolus suppresses uncontrolled recombination. However, broken repeats must be first released to the nucleoplasm to allow repair by homologous recombination. Nucleolar relea...
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Nucleolar release of rDNA repeats for repair involves SUMO-mediated untethering by the Cdc48/p97 segregase
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TN_cdi_doaj_primary_oai_doaj_org_article_7c25cbe4fae14af59e6291014ce9f3bc
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c25cbe4fae14af59e6291014ce9f3bc
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25205-2
