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Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and hu...

Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and hu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c5db71c472645af80c01089faaa997c

Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies

About this item

Full title

Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies

Publisher

England: BioMed Central Ltd

Journal title

Fluids and barriers of the CNS, 2024-07, Vol.21 (1), p.58-17, Article 58

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Structural and functional changes of the choroid plexus (ChP) have been reported in Alzheimer's disease (AD). Nonetheless, the role of the ChP in the pathogenesis of AD remains largely unknown. We aim to unravel the relation between ChP functioning and core AD pathogenesis using a unique proteomic approach in mice and humans.
We used an APP knoc...

Alternative Titles

Full title

Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7c5db71c472645af80c01089faaa997c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c5db71c472645af80c01089faaa997c

Other Identifiers

ISSN

2045-8118

E-ISSN

2045-8118

DOI

10.1186/s12987-024-00555-3