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Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acu...

Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c6c1b001dcc4d3dbad39bcf10b7293b

Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

About this item

Full title

Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

Publisher

England: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2020-07, Vol.17 (1), p.227-227, Article 227

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Neuronal damage in acute CNS injuries and chronic neurodegenerative diseases is invariably accompanied by an astrocyte reaction in both mice and humans. However, whether and how the nature of the CNS insult-acute versus chronic-influences the astrocyte response, and whether astrocyte transcriptomic changes in these mouse models faithfully recapitul...

Alternative Titles

Full title

Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7c6c1b001dcc4d3dbad39bcf10b7293b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c6c1b001dcc4d3dbad39bcf10b7293b

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-020-01898-y

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