ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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The receptor tyrosine kinase-like orphan receptor 1 (ROR1) sustains prosurvival signalling directly downstream of the lineage-survival oncogene NKX2-1/TTF-1 in lung adenocarcinoma. Here we report an unanticipated function of this receptor tyrosine kinase (RTK) as a scaffold of cavin-1 and caveolin-1 (CAV1), two essential structural components of ca...
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Full title
ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
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TN_cdi_doaj_primary_oai_doaj_org_article_7c75a87e81e0429b80dd4b3a91b33ba8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c75a87e81e0429b80dd4b3a91b33ba8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10060
