CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal c...
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Immune homeostasis in intestinal tissues depends on the generation of regulatory T (Treg) cells. CD103
+
dendritic cells (DCs) acquire microbiota-derived material from the gut lumen for transport to draining lymph nodes and generation of receptor-related orphan γt
+
(RORγt
+
) Helios
−
-induced Treg (iTreg) cells. Here we sh...
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Full title
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis
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TN_cdi_doaj_primary_oai_doaj_org_article_7c8b4bc021104cd99b9d6bf8099e2013
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7c8b4bc021104cd99b9d6bf8099e2013
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14715