SIRT4 silencing in tumor-associated macrophages promotes HCC development via PPARδ signalling-mediat...
SIRT4 silencing in tumor-associated macrophages promotes HCC development via PPARδ signalling-mediated alternative activation of macrophages
About this item
Full title
Author / Creator
Li, Zhi , Li, He , Zhao, Zhi-Bo , Zhu, Wei , Feng, Pan-Pan , Zhu, Xi-Wen and Gong, Jian-Ping
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The activation of tumour-associated macrophages (TAMs) contributes to the progression of hepatocellular carcinoma (HCC). SIRT4 acts as a tumour suppressor of tumour growth by regulating cell metabolism, inflammation, and anti-tumourigenesis. However, the involvement of SIRT4 in the activation of TAMs is unknown. Based on previous findings, the expr...
Alternative Titles
Full title
SIRT4 silencing in tumor-associated macrophages promotes HCC development via PPARδ signalling-mediated alternative activation of macrophages
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7cb3164660ba46ff89cdb620ddb74232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7cb3164660ba46ff89cdb620ddb74232
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-019-1456-9
