DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death
About this item
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Author / Creator
Low, Heng Boon , Wong, Zhen Lim , Wu, Bangyuan , Kong, Li Ren , Png, Chin Wen , Cho, Yik-Lam , Li, Chun-Wei , Xiao, Fengchun , Xin, Xuan , Yang, Henry , Loo, Jia Min , Lee, Fiona Yi Xin , Tan, Iain Bee Huat , DasGupta, Ramanuj , Shen, Han-Ming , Schwarz, Herbert , Gascoigne, Nicholas R. J. , Goh, Boon Cher , Xu, Xiaohong and Zhang, Yongliang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Drug resistance is a major obstacle to the treatment of most human tumors. In this study, we find that dual-specificity phosphatase 16 (DUSP16) regulates resistance to chemotherapy in nasopharyngeal carcinoma, colorectal cancer, gastric and breast cancer. Cancer cells expressing higher DUSP16 are intrinsically more resistant to chemotherapy-induced...
Alternative Titles
Full title
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death
Authors, Artists and Contributors
Author / Creator
Wong, Zhen Lim
Wu, Bangyuan
Kong, Li Ren
Png, Chin Wen
Cho, Yik-Lam
Li, Chun-Wei
Xiao, Fengchun
Xin, Xuan
Yang, Henry
Loo, Jia Min
Lee, Fiona Yi Xin
Tan, Iain Bee Huat
DasGupta, Ramanuj
Shen, Han-Ming
Schwarz, Herbert
Gascoigne, Nicholas R. J.
Goh, Boon Cher
Xu, Xiaohong
Zhang, Yongliang
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7cd1e1ed821d475f86d18b8927eabe0d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7cd1e1ed821d475f86d18b8927eabe0d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22638-7
