Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice
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Author / Creator
Spix, Barbara , Butz, Elisabeth S. , Chen, Cheng-Chang , Rosato, Anna Scotto , Tang, Rachel , Jeridi, Aicha , Kudrina, Veronika , Plesch, Eva , Wartenberg, Philipp , Arlt, Elisabeth , Briukhovetska, Daria , Ansari, Meshal , Günsel, Gizem Günes , Conlon, Thomas M. , Wyatt, Amanda , Wetzel, Sandra , Teupser, Daniel , Holdt, Lesca M. , Ectors, Fabien , Boekhoff, Ingrid , Boehm, Ulrich , García-Añoveros, Jaime , Saftig, Paul , Giera, Martin , Kobold, Sebastian , Schiller, Herbert B. , Zierler, Susanna , Gudermann, Thomas , Wahl-Schott, Christian , Bracher, Franz , Yildirim, Ali Önder , Biel, Martin and Grimm, Christian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Lung emphysema and chronic bronchitis are the two most common causes of chronic obstructive pulmonary disease. Excess macrophage elastase MMP-12, which is predominantly secreted from alveolar macrophages, is known to mediate the development of lung injury and emphysema. Here, we discovered the endolysosomal cation channel mucolipin 3 (TRPML3) as a...
Alternative Titles
Full title
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice
Authors, Artists and Contributors
Author / Creator
Butz, Elisabeth S.
Chen, Cheng-Chang
Rosato, Anna Scotto
Tang, Rachel
Jeridi, Aicha
Kudrina, Veronika
Plesch, Eva
Wartenberg, Philipp
Arlt, Elisabeth
Briukhovetska, Daria
Ansari, Meshal
Günsel, Gizem Günes
Conlon, Thomas M.
Wyatt, Amanda
Wetzel, Sandra
Teupser, Daniel
Holdt, Lesca M.
Ectors, Fabien
Boekhoff, Ingrid
Boehm, Ulrich
García-Añoveros, Jaime
Saftig, Paul
Giera, Martin
Kobold, Sebastian
Schiller, Herbert B.
Zierler, Susanna
Gudermann, Thomas
Wahl-Schott, Christian
Bracher, Franz
Yildirim, Ali Önder
Biel, Martin
Grimm, Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7d029bd581f74fcaa96bcacc1faef5b8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7d029bd581f74fcaa96bcacc1faef5b8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27860-x
