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Fighting in a wasteland: deleterious metabolites and antitumor immunity

Fighting in a wasteland: deleterious metabolites and antitumor immunity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7dfc5207a01a4511bfc6479aff5b3684

Fighting in a wasteland: deleterious metabolites and antitumor immunity

About this item

Full title

Fighting in a wasteland: deleterious metabolites and antitumor immunity

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2022-01, Vol.132 (2), p.1-11

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

As cancers progress, they produce a local environment that acts to redirect, paralyze, exhaust, or otherwise evade immune detection and destruction. The tumor microenvironment (TME) has long been characterized as a metabolic desert, depleted of essential nutrients such as glucose, oxygen, and amino acids, that starves infiltrating immune cells and...

Alternative Titles

Full title

Fighting in a wasteland: deleterious metabolites and antitumor immunity

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7dfc5207a01a4511bfc6479aff5b3684

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7dfc5207a01a4511bfc6479aff5b3684

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI148549

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