Fighting in a wasteland: deleterious metabolites and antitumor immunity
Fighting in a wasteland: deleterious metabolites and antitumor immunity
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United States: American Society for Clinical Investigation
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English
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United States: American Society for Clinical Investigation
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Contents
As cancers progress, they produce a local environment that acts to redirect, paralyze, exhaust, or otherwise evade immune detection and destruction. The tumor microenvironment (TME) has long been characterized as a metabolic desert, depleted of essential nutrients such as glucose, oxygen, and amino acids, that starves infiltrating immune cells and...
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Fighting in a wasteland: deleterious metabolites and antitumor immunity
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TN_cdi_doaj_primary_oai_doaj_org_article_7dfc5207a01a4511bfc6479aff5b3684
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7dfc5207a01a4511bfc6479aff5b3684
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI148549