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Reference EntriesFull Text
Delgoffe, Greg M
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: COO-DUQ, 2022, p.2707-2707
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Reference EntriesFull Text
Delgoffe, Greg M
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: COO-DUQ, 2021, p.2693-2693
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Newsletter articlesFull Text
INTERNATIONAL PATENT: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, DELGOFFE, GREG, M., PERALTA, RONAL FILES APPLICATION FOR "MCT11 ANTIBODIES TO TREAT T CELL FUNCTIONAL E...
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2023
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ArticlesPeer ReviewedFull Text
Fighting in a wasteland: deleterious metabolites and antitumor immunity
Author / Creator:Watson, McLane J. ; Delgoffe, Greg M.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-01, Vol.132 (2), p.1-11
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ArticlesPeer ReviewedFull Text
Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity
Author / Creator:Vignali, Paolo D. A. ; DePeaux, Kristin ; Watson, McLane J. ; Ye, Chenxian ; Ford, B. Rhodes ; Lontos, Konstantinos ; McGaa, Nicole K. ; Scharping, Nicole E. ; Menk, Ashley V. ; Robson, Simon C. ; Poholek, Amanda C. ; Rivadeneira, Dayana B. ; Delgoffe, Greg M.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2023-02, Vol.24 (2), p.267-279
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ArticlesPeer ReviewedFull Text
Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis
Author / Creator:Weisel, Florian J. ; Mullett, Steven J. ; Elsner, Rebecca A. ; Menk, Ashley V. ; Trivedi, Nikita ; Luo, Wei ; Wikenheiser, Daniel ; Hawse, William F. ; Chikina, Maria ; Smita, Shuchi ; Conter, Laura J. ; Joachim, Stephen M. ; Wendell, Stacy G. ; Jurczak, Michael J. ; Winkler, Thomas H. ; Delgoffe, Greg M. ; Shlomchik, Mark J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-03, Vol.21 (3), p.331-342
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ArticlesPeer ReviewedFull Text
The composition and signaling of the IL-35 receptor are unconventional
Author / Creator:Collison, Lauren W ; Delgoffe, Greg M ; Guy, Clifford S ; Vignali, Kate M ; Chaturvedi, Vandana ; Fairweather, DeLisa ; Satoskar, Abhay R ; Garcia, K Christopher ; Hunter, Christopher A ; Drake, Charles G ; Murray, Peter J ; Vignali, Dario A A
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2012-03, Vol.13 (3), p.290-299
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ArticlesPeer ReviewedFull Text
Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck
Author / Creator:Zandberg, Dan P ; Menk, Ashley V ; Velez, Maria ; Normolle, Daniel ; DePeaux, Kristin ; Liu, Angen ; Ferris, Robert L ; Delgoffe, Greg M
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-05, Vol.9 (5), p.e002088
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ArticlesPeer ReviewedFull Text
Metabolic barriers to cancer immunotherapy
Author / Creator:DePeaux, Kristin ; Delgoffe, Greg M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2021-12, Vol.21 (12), p.785-797
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ArticlesPeer ReviewedFull Text
Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors
Author / Creator:Lontos, Konstantinos ; Wang, Yiyang ; Joshi, Supriya K ; Frisch, Andrew T ; Watson, McLane J ; Kumar, Alok ; Menk, Ashley V ; Wang, Yupeng ; Cumberland, Rachel ; Lohmueller, Jason ; Carrizosa, Esteban ; Boyerinas, Benjamin ; Delgoffe, Greg M
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-03, Vol.11 (3), p.e006522
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ArticlesPeer ReviewedFull Text
Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection
Author / Creator:Carreno-Florez, Grace P. ; Kocak, Brian R. ; Hendricks, Matthew R. ; Melvin, Jeffrey A. ; Mar, Katrina B. ; Kosanovich, Jessica ; Cumberland, Rachel L. ; Delgoffe, Greg M. ; Shiva, Sruti ; Empey, Kerry M. ; Schoggins, John W. ; Bomberger, Jennifer M.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-11, Vol.19 (11), p.e1011719-e1011719
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ArticlesPeer ReviewedFull Text
Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells
Author / Creator:DePeaux, Kristin ; Gunn, William G ; Rivadeneira, Dayana B ; Delgoffe, Greg M
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2024-08, Vol.12 (8), p.e009062
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ArticlesPeer ReviewedFull Text
Metabolic waypoints during T cell differentiation
Author / Creator:Wilfahrt, Drew ; Delgoffe, Greg M.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2024-02, Vol.25 (2), p.206-217
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ArticlesPeer ReviewedFull Text
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
Author / Creator:Downs-Canner, Stephanie ; Berkey, Sara ; Delgoffe, Greg M. ; Edwards, Robert P. ; Curiel, Tyler ; Odunsi, Kunle ; Bartlett, David L. ; Obermajer, Nataša
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-03, Vol.8 (1), p.14649-14649, Article 14649
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ArticlesPeer ReviewedFull Text
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion
Author / Creator:Scharping, Nicole E. ; Rivadeneira, Dayana B. ; Menk, Ashley V. ; Vignali, Paolo D. A. ; Ford, B. Rhodes ; Rittenhouse, Natalie L. ; Peralta, Ronal ; Wang, Yiyang ; Wang, Yupeng ; DePeaux, Kristin ; Poholek, Amanda C. ; Delgoffe, Greg M.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2021-02, Vol.22 (2), p.205-215
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ArticlesPeer ReviewedFull Text
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid
Author / Creator:Watson, McLane J. ; Vignali, Paolo D. A. ; Mullett, Steven J. ; Overacre-Delgoffe, Abigail E. ; Peralta, Ronal M. ; Grebinoski, Stephanie ; Menk, Ashley V. ; Rittenhouse, Natalie L. ; DePeaux, Kristin ; Whetstone, Ryan D. ; Vignali, Dario A. A. ; Hand, Timothy W. ; Poholek, Amanda C. ; Morrison, Brett M. ; Rothstein, Jeffrey D. ; Wendell, Stacy G. ; Delgoffe, Greg M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-03, Vol.591 (7851), p.645-651
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ArticlesPeer ReviewedFull Text
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours
Author / Creator:Zappasodi, Roberta ; Serganova, Inna ; Cohen, Ivan J. ; Maeda, Masatomo ; Shindo, Masahiro ; Senbabaoglu, Yasin ; Watson, McLane J. ; Leftin, Avigdor ; Maniyar, Rachana ; Verma, Svena ; Lubin, Matthew ; Ko, Myat ; Mane, Mayuresh M. ; Zhong, Hong ; Liu, Cailian ; Ghosh, Arnab ; Abu-Akeel, Mohsen ; Ackerstaff, Ellen ; Koutcher, Jason A. ; Ho, Ping-Chih ; Delgoffe, Greg M. ; Blasberg, Ronald ; Wolchok, Jedd D. ; Merghoub, Taha
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-03, Vol.591 (7851), p.652-658
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ArticlesPeer ReviewedFull Text
mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
Author / Creator:Pollizzi, Kristen N. ; Patel, Chirag H. ; Sun, Im-Hong ; Oh, Min-Hee ; Waickman, Adam T. ; Wen, Jiayu ; Delgoffe, Greg M. ; Powell, Jonathan D.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-05, Vol.125 (5), p.2090-2108
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ArticlesPeer ReviewedFull Text
Characteristics of the Tumor Microenvironment That Influence Immune Cell Functions: Hypoxia, Oxidative Stress, Metabolic Alterations
Author / Creator:Augustin, Ryan C. ; Delgoffe, Greg M. ; Najjar, Yana G.
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2020-12, Vol.12 (12), p.3802
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ArticlesPeer ReviewedFull Text
Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)
Author / Creator:Ascierto, Paolo A. ; Bifulco, Carlo ; Buonaguro, Luigi ; Emens, Leisha A. ; Ferris, Robert L. ; Fox, Bernard A. ; Delgoffe, Greg M. ; Galon, Jérôme ; Gridelli, Cesare ; Merlano, Marco ; Nathan, Paul ; Odunsi, Kunle ; Okada, Hideho ; Paulos, Chrystal M. ; Pignata, Sandro ; Schalper, Kurt A. ; Spranger, Stefani ; Tortora, Giampaolo ; Zarour, Hassane ; Butterfield, Lisa H. ; Puzanov, Igor
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2019-11, Vol.7 (1), p.332-332, Article 332
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Delgoffe, Greg M

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Delgoffe, Greg M

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INTERNATIONAL PATENT: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, DELGOFFE, GREG, M., PERALTA, RONAL FILES APPLICATION FOR "MCT11 ANTIBODIES TO TREAT T CELL FUNCTIONAL E...

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Fighting in a wasteland: deleterious metabolites and antitumor immunity

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Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

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Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis

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The composition and signaling of the IL-35 receptor are unconventional

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Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck

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Metabolic barriers to cancer immunotherapy

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Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors

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Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection

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Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells

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Metabolic waypoints during T cell differentiation

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Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells

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Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

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Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

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CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours

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mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation

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Characteristics of the Tumor Microenvironment That Influence Immune Cell Functions: Hypoxia, Oxidative Stress, Metabolic Alterations

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Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge 2018” (28–29 November, 2018, Naples, Italy)

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