The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondri...
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism
About this item
Full title
Author / Creator
Stuhldreier, Fabian , Schmitt, Laura , Lenz, Thomas , Hinxlage, Ilka , Zimmermann, Marcel , Wollnitzke, Philipp , Schliehe-Diecks, Julian , Liu, Yang , Jäger, Paul , Geyh, Stefanie , Teusch, Nicole , Peter, Christoph , Bhatia, Sanil , Haas, Rainer , Levkau, Bodo , Reichert, Andreas S. , Stühler, Kai , Proksch, Peter , Stork, Björn and Wesselborg, Sebastian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Inhibition of the mitochondrial metabolism offers a promising therapeutic approach for the treatment of cancer. Here, we identify the mycotoxin viriditoxin (VDT), derived from the endophytic fungus
Cladosporium cladosporioides
, as an interesting candidate for leukemia and lymphoma treatment. VDT displayed a high cytotoxic potential and rapid...
Alternative Titles
Full title
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism
Authors, Artists and Contributors
Author / Creator
Schmitt, Laura
Lenz, Thomas
Hinxlage, Ilka
Zimmermann, Marcel
Wollnitzke, Philipp
Schliehe-Diecks, Julian
Liu, Yang
Jäger, Paul
Geyh, Stefanie
Teusch, Nicole
Peter, Christoph
Bhatia, Sanil
Haas, Rainer
Levkau, Bodo
Reichert, Andreas S.
Stühler, Kai
Proksch, Peter
Stork, Björn
Wesselborg, Sebastian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7e96c5faca6e4597a6d4c5bd9fe0a680
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e96c5faca6e4597a6d4c5bd9fe0a680
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-05356-w
