Item-level analyses reveal genetic heterogeneity in neuroticism
Item-level analyses reveal genetic heterogeneity in neuroticism
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Genome-wide association studies (GWAS) of psychological traits are generally conducted on (dichotomized) sums of items or symptoms (e.g., case-control status), and not on the individual items or symptoms themselves. We conduct large-scale GWAS on 12 neuroticism items and observe notable and replicable variation in genetic signal between items. With...
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Full title
Item-level analyses reveal genetic heterogeneity in neuroticism
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TN_cdi_doaj_primary_oai_doaj_org_article_7e9fd55c065d4717ac52709cbb4a6ab9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7e9fd55c065d4717ac52709cbb4a6ab9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03242-8
