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Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cell...

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f189439f64c4318ac3cf0baaa3c3614

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

About this item

Full title

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-11, Vol.8 (1), p.1576-13, Article 1576

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dysregulation of autophagy and inflammasome activity contributes to the development of auto-inflammatory diseases. Emerging evidence highlights the importance of the actin cytoskeleton in modulating inflammatory responses. Here we show that deficiency of Wiskott–Aldrich syndrome protein (WASp), which signals to the actin cytoskeleton, modulates aut...

Alternative Titles

Full title

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7f189439f64c4318ac3cf0baaa3c3614

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f189439f64c4318ac3cf0baaa3c3614

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-01676-0

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