Pharmacological Modulation of Rate-Dependent Depression of the Spinal H-Reflex Predicts Therapeutic...
Pharmacological Modulation of Rate-Dependent Depression of the Spinal H-Reflex Predicts Therapeutic Efficacy against Painful Diabetic Neuropathy
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Switzerland: MDPI
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English
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Switzerland: MDPI
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Impaired rate-dependent depression (RDD) of the spinal H-reflex occurs in diabetic rodents and a sub-set of patients with painful diabetic neuropathy. RDD is unaffected in animal models of painful neuropathy associated with peripheral pain mechanisms and diabetic patients with painless neuropathy, suggesting RDD could serve as a biomarker for indiv...
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Full title
Pharmacological Modulation of Rate-Dependent Depression of the Spinal H-Reflex Predicts Therapeutic Efficacy against Painful Diabetic Neuropathy
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TN_cdi_doaj_primary_oai_doaj_org_article_7f623f77f95e4d829fdce86e2893b517
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f623f77f95e4d829fdce86e2893b517
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ISSN
2075-4418
E-ISSN
2075-4418
DOI
10.3390/diagnostics11020283
