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Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f85d4fa82924e2aa5b4c4178b64f9e3

Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

About this item

Full title

Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Publisher

South Africa: African Online Scientific Information Systems (Pty) Ltd t/a AOSIS

Journal title

Southern African journal of HIV medicine, 2021, Vol.22 (1), p.1206-e24

Language

English

Formats

Publication information

Publisher

South Africa: African Online Scientific Information Systems (Pty) Ltd t/a AOSIS

More information

Scope and Contents

Contents

Blood-cerebrospinal fluid (CSF) barrier transporters affect the influx and efflux of drugs. The antiretrovirals tenofovir and emtricitabine may be substrates of blood-brain barrier (BBB) and blood-CSF barrier transporters, but data are limited regarding the pharmacogenetics and pharmacokinetics of their central nervous system (CNS) penetration.
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Alternative Titles

Full title

Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7f85d4fa82924e2aa5b4c4178b64f9e3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7f85d4fa82924e2aa5b4c4178b64f9e3

Other Identifiers

ISSN

1608-9693,2078-6751

E-ISSN

2078-6751

DOI

10.4102/sajhivmed.v22i1.1206

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